Volume 23, Issue 27 (2-2025)                   JNIP 2025, 23(27): 1-26 | Back to browse issues page

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Sameni M. The Comparison of Prefrontal Cortex Function in Patients with Generalized Anxiety Disorder and Social Anxiety Disorder with Healthy Group. JNIP 2025; 23 (27) :1-26
URL: http://jnip.ir/article-1-1337-en.html
Abstract:   (15 Views)
Anxiety disorders are one of the most challenging disorders in the field of mental health. Generalized anxiety disorder and social anxiety disorder are among the most common disorders in the spectrum of anxiety disorders. Considering the role of the prefrontal cortex in executive functions and cognitive control, this study aimed to investigate the role of the prefrontal cortex in patients with generalized anxiety disorder and social anxiety disorder compared to healthy individuals. The present study is a correlational and causal-comparative design, the participants of which are: 30 patients with generalized anxiety disorder, 30 patients with social anxiety disorder, and 30 healthy control group. At first, the function of the prefrontal cortex of the brain in patients with generalized anxiety disorder and social anxiety disorder was measured using Wisconsin cards test; Then, a test was taken from the healthy control group, and the test results of the two groups of patients and the healthy group were analyzed with the Kruskal-Wallis test and the comparison of the function of the prefrontal cortex of the brain in two groups of patients with generalized anxiety disorder and social anxiety was analyzed using the Mann-Whitney test. The results showed that from the main items of the Wisconsin test, there were more errors in remaining and the number of completed classes was less in the group of sick people than in healthy people. Which shows that the functions of cognitive flexibility and conceptualization are at a much lower level in the group of sick people. The deficit in cognitive flexibility and conceptualization is related to the dysfunction of the dorsolateral cortex of the frontal lobe. Paying attention to this area of ​​the brain can improve psychological treatments, especially in the field of neuropsychology.
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Type of Study: Research | Subject: Special
Received: 2025/09/26 | Revised: 2025/09/26 | Accepted: 2025/02/28 | Published: 2025/02/28

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